MAX-40279, CAS [[2070931-57-4]]

Product Overview

• Article Name: MAX-40279, CAS [[2070931-57-4]]
• Biozol Catalog Number: MCE-HY-145723
• Supplier Catalog Number: HY-145723
• Alternative Catalog Number: MCE-HY-145723-5MG,MCE-HY-145723-10MG,MCE-HY-145723-10MMX1ML,MCE-HY-145723-25MG,MCE-HY-145723-50MG,MCE-HY-145723-100MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

MAX-40279 is a dual and orally active inhibitor of FLT3 kinase and FGFR kinase. MAX-40279 is also effective against the FLT3 mutants such as FLT3D835Y, suggesting that it can overcome resistance to Quizartinib (HY-13001) and Sorafenib (HY-10201). MAX-40279 inhibits NDRG1 phosphorylation at Ser330 and suppresses endothelial-to-mesenchymal transition (EndMT). MAX-40279 can be used for the research of acute myelogenous leukemia (AML)[1][2][3].

Product Properties

• Molecular Weight: 438.52
• Purity: 97.04
• CAS Number: [2070931-57-4]
• Formula: C22H23FN6OS
• Target: FGFR,FLT3

Application Notes

• Application Notes: MCE Product type: Reference compound