JPS016 is a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimeras (PROTAC). JPS016 degrades class I histone deacetylase (HDAC). JPS016 is potent HDAC1/2 degrader correlated with greater total differentially expressed genes and enhanced apoptosis in HCT116 cells[1].
Molecular Weight:
1012.14
Purity:
99.47
Formula:
C50H64F3N7O10S
Target:
HDAC,PROTACs
Application Notes:
MCE Product type: Reference compound
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