(rac)-Talazoparib, CAS [[1207454-56-5]] Preis auf Anfrage

Product Overview

• Article Name: (rac)-Talazoparib, CAS [[1207454-56-5]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-14687
• Supplier Catalog Number: HY-14687
• Alternative Catalog Number: MCE-HY-14687-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: (rac)-BMN-673, (rac)-LT-673

Product Description

(rac)-Talazoparib ((rac)-BMN-673) (Compound 47) is the orally active inhibitor for PARP1/2 with Ki of 1.2 nM and 0.87 nM. (rac)-Talazoparib inhibits cellular PARylation with an EC50 of 2.51 nM. (rac)-Talazoparib causes the accumulation of DNA damage, inhibits proliferation of BRCA1/2-mutated MX-1 cell and Capan-1 cell with IC50 of 0.3 nM and 5 nM. (rac)-Talazoparib exhibits antitumor efficacy in mouse models[1].

Product Properties

• Molecular Weight: 380.35
• CAS Number: [1207454-56-5]
• Formula: C19H14F2N6O
• Target: PARP

Application Notes

• Application Notes: Reference compound