MDH1-IN-2, CAS [[2143463-35-6]]

Product Overview

• Article Name: MDH1-IN-2, CAS [[2143463-35-6]]
• Biozol Catalog Number: MCE-HY-147791
• Supplier Catalog Number: HY-147791
• Alternative Catalog Number: MCE-HY-147791-5MG,MCE-HY-147791-10MMX1ML,MCE-HY-147791-10MG,MCE-HY-147791-25MG,MCE-HY-147791-50MG,MCE-HY-147791-100MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

MDH1-IN-2 (Compound 7c) is a selective MDH1 inhibitor, with IC50 values of 2.27 and 27.47 µM for MDH1 and MDH2, respectively. MDH1-IN-2 can reduce the generation of ROS by inhibiting the conversion of 2-Ketoglutaric acid (HY-W013636) to alpha-Hydroxyglutaric acid (HY-113038B) mediated by MDH1, thereby suppressing 2-Ketoglutaric acid (HY-W013636)-induced ferroptosis[1][2].

Product Properties

• Molecular Weight: 427.53
• Purity: 98.70
• CAS Number: [2143463-35-6]
• Formula: C25H33NO5
• Target: Ferroptosis,Malate Dehydrogenase (MDH),Reactive Oxygen Species (ROS)

Application Notes

• Application Notes: MCE Product type: Reference compound1