BI-0474, CAS [[2750570-55-7]]

Product Overview

• Article Name: BI-0474, CAS [[2750570-55-7]]
• Biozol Catalog Number: MCE-HY-148278
• Supplier Catalog Number: HY-148278
• Alternative Catalog Number: MCE-HY-148278-100MG,MCE-HY-148278-50MG,MCE-HY-148278-10MMX1ML,MCE-HY-148278-10MG,MCE-HY-148278-5MG,MCE-HY-148278-25MG,MCE-HY-148278-250MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

BI-0474 is a potent KRASG12C inhibitor with an IC50 value of 7.0 nM for the GDP-KRAS::SOS1 protein-protein interaction. BI-0474 exhibits good anti-proliferative activity against NCI-H358 cells carrying the G12C mutation. BI-0474 also shows good anti-tumour activity in non-small cell lung cancer xenograft models[1].

Product Properties

• Molecular Weight: 587.74
• Purity: 99.83
• CAS Number: [2750570-55-7]
• Formula: C30H37N9O2S
• Target: Ras,SOS1

Application Notes

• Application Notes: MCE Product type: Reference compound