EZH2-IN-14 is a selective EZH2 (Histone Methyltransferase) inhibitor with an IC50 of 12 nM. EZH2-IN-14 inhibits the methyltransferase activity of EZH2/PRC2 (that is, reducing H3K27me3). EZH2-IN-14 shows >200-fold selective for EZH2 over the highly homologous H3K27 methyltransferase EZH1[1].
Molecular Weight:
541.69
Purity:
99.62
CAS Number:
[1979157-17-9]
Formula:
C31H39N7O2
Target:
Histone Methyltransferase
Application Notes:
MCE Product type: Reference compound
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