YX-2-107 is a PROTAC (IC50= 4.4 nM) that selectively degrades CDK6. YX-2-107 effectively inhibits RB phosphorylation and FOXM1 expression in vitro and inhibits the development of Ph+ ALL in rats. YX-2-107 can be used in the study of Ph chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL)[1].
Molecular Weight:
889.95
Purity:
99.22
CAS Number:
[2417408-46-7]
Formula:
C45H51N11O9
Target:
CDK,PROTACs
Application Notes:
MCE Product type: Reference compound
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