LY3522348, CAS [[2568608-48-8]]

Product Overview

• Article Name: LY3522348, CAS [[2568608-48-8]]
• Biozol Catalog Number: MCE-HY-149987
• Supplier Catalog Number: HY-149987
• Alternative Catalog Number: MCE-HY-149987-10MMX1ML,MCE-HY-149987-1G,MCE-HY-149987-500MG,MCE-HY-149987-5MG,MCE-HY-149987-100MG,MCE-HY-149987-50MG,MCE-HY-149987-10MG,MCE-HY-149987-250MG,MCE-HY-149987-25MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: KHK-IN-3

Product Description

KHK-IN-3 (Example 1) is a ketohexokinase (KHK) inhibitor. KHK-IN-3 can be used in the study of kidney disease, nonalcoholic steatohepatitis (NASH), diabetes and heart failure. KHK is a rate-limiting enzyme and fructokinase involved in fructose metabolism. KHK catalyzes the phosphorylation of fructose to fructose-1-phosphate (FIP) at the expense of ATP. The lack of feedback inhibition of fructose metabolism triggers the accumulation of downstream intermediates such as lipogenesis, gluconeogenesis, and oxidative phosphorylation[1].

Product Properties

• Molecular Weight: 409.41
• Purity: 98.30
• CAS Number: [2568608-48-8]
• Formula: C18H22F3N7O
• Target: Ketohexokinase

Application Notes

• Application Notes: MCE Product type: Reference compound