BI-1622, CAS [[2681392-19-6]]

Product Overview

• Article Name: BI-1622, CAS [[2681392-19-6]]
• Biozol Catalog Number: MCE-HY-150023
• Supplier Catalog Number: HY-150023
• Alternative Catalog Number: MCE-HY-150023-5MG,MCE-HY-150023-25MG,MCE-HY-150023-10MMX1ML,MCE-HY-150023-50MG,MCE-HY-150023-100MG,MCE-HY-150023-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

BI-1622 is an orally active, potent and highly selective HER2 (ERBB2) inhibitor, with an IC50 of 7 nM. BI-1622 shows greater than 25-fold selectivity over EGFR. BI-1622 shows high antitumor efficacy in vivo in xenograft mouse tumor models with engineered H2170 and PC9 cells and had a favorable agent metabolism and pharmacokinetics profile[1].

Product Properties

• Molecular Weight: 508.53
• Purity: 98.97
• CAS Number: [2681392-19-6]
• Formula: C26H24N10O2
• Target: Btk,CDK,EGFR,Itk,JAK,PI4K,Raf

Application Notes

• Application Notes: MCE Product type: Reference compound