Purinostat, CAS [[1929583-17-4]]

Product Overview

• Article Name: Purinostat, CAS [[1929583-17-4]]
• Biozol Catalog Number: MCE-HY-150109A
• Supplier Catalog Number: HY-150109A
• Alternative Catalog Number: MCE-HY-150109A-10MG,MCE-HY-150109A-100MG,MCE-HY-150109A-5MG,MCE-HY-150109A-50MG,MCE-HY-150109A-25MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

Purinostat is a selective inhibitor of HDAC I/IIb with anti-leukemic activity. Purinostat mesylate (HY-150109), the mesylate salt of Purinostat, inhibits the survival of Ph+ leukemic cells and CD34+ leukemic cells derived from CML patients. Purinostat mesylate targets HDAC I/IIb to inhibit several important factors for leukemic stem cell (LSC) survival, including c-Myc, beta-Catenin, E2f, Ezh2, Alox5, and mTOR. Purinostat mesylate increases glutamate metabolism in LSC by increasing GLS1[1].

Product Properties

• Molecular Weight: 490.52
• Purity: 98.04
• CAS Number: [1929583-17-4]
• Formula: C23H26N10O3
• Target: HDAC

Application Notes

• Application Notes: MCE Product type: Reference compound1