Pyridostatin (RR82) is a G-quadruplex DNA stabilizing agent (Kd=490 nM) and can target DNA and RNA G4s in cells. Pyridostatin promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin targets the proto-oncogene Src. Pyridostatin reduced SRC protein levels and SRC-dependent cellular motility in human breast cancer cells[1][2].
Molecular Weight:
596.64
Purity:
96.03
CAS Number:
[1085412-37-8]
Formula:
C31H32N8O5
Target:
G-quadruplex
Application Notes:
MCE Product type: Reference compound
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