Zefamenib (BN-104) is an effective selective brain membrane protein inhibitor with oral activity, and its also a Menin inhibitor, it can block the Menin-MLL interaction and leads to the degradation of Menin protein. Zefamenib is a weak hERG inhibitor, with an IC50 greater than 100 µM. Zefamenib has anti-tumor activity and can be used in cancer research, such as for acute myeloid leukemia[1].
Molecular Weight:
570.66
Purity:
99.95
CAS Number:
[2938995-50-5]
Formula:
C31H35FN8O2
Target:
Epigenetic Reader Domain,Potassium Channel
Application Notes:
MCE Product type: Reference compound
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