PF-543 (Citrate), CAS [[1415562-83-2]]

Product Overview

• Article Name: PF-543 (Citrate), CAS [[1415562-83-2]]
• Biozol Catalog Number: MCE-HY-15425A
• Supplier Catalog Number: HY-15425A
• Alternative Catalog Number: MCE-HY-15425A-5MG,MCE-HY-15425A-50MG,MCE-HY-15425A-10MMX1ML,MCE-HY-15425A-100MG,MCE-HY-15425A-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: Sphingosine Kinase 1 Inhibitor II (Citrate)

Product Description

PF-543 Citrate (Sphingosine Kinase 1 Inhibitor II Citrate) is a potent, selective, reversible and sphingosine-competitive SPHK1 inhibitor with an IC50 of 2 nM and a Ki of 3.6 nM. PF-543 Citrate is >100-fold selectivity for SPHK1 over SPHK2. PF-543 Citrate is an effective potent inhibitor of sphingosine 1-phosphate (S1P) formation in whole blood with an IC50 of 26.7 nM. PF-543 Citrate induces apoptosis, necrosis, and autophagy[1][2][3].

Product Properties

• Molecular Weight: 657.73
• Purity: 99.47
• CAS Number: [1415562-83-2]
• Formula: C33H39NO11S
• Target: Apoptosis,Autophagy,LPL Receptor,SphK

Application Notes

• Application Notes: MCE Product type: Reference compound