EGFR/AURKB-IN-1, CAS [[3008543-34-5]]

Product Overview

• Article Name: EGFR/AURKB-IN-1, CAS [[3008543-34-5]]
• Biozol Catalog Number: MCE-HY-157480
• Supplier Catalog Number: HY-157480
• Alternative Catalog Number: MCE-HY-157480-10MG,MCE-HY-157480-5MG,MCE-HY-157480-25MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

EGFR/AURKB-IN-1 (compound 7) is a dual-targeted EGFR/AURKB inhibitor, and inhibits the phpsphorylations of L858R EGFR and AURKB with IC50s of 0.07 and 1.1, respectively. EGFR/AURKB-IN-1 occupies the hydrophobic region I or the alphaC-helix out pocket of EGFR and the back pocket of AURKB, inhibiting the growth, division and metastasis of tumor cells, thus can be used for cancer research[1].

Product Properties

• Molecular Weight: 396.44
• Purity: 99.43
• CAS Number: [3008543-34-5]
• Formula: C23H20N6O
• Target: Aurora Kinase,EGFR

Application Notes

• Application Notes: MCE Product type: Reference compound