PROTAC K-Ras Degrader-4 (Compound 4) is a PROTAC degrader for KRAS that degrades KRASG12D in GP5d and degrades KRASG12V in cell SW620 with DC50s of 1 nM and 13 nM. PROTAC K-Ras Degrader-4 inhibits MAPK signaling pathway[1]. (Pink: ligand for target protein pan-KRAS degrader 1 (HY-162960), Black: linker (HY-159790), Blue: ligand for E3 ligase VHL (HY-W998248))
Molecular Weight:
989.22
Purity:
99.01
CAS Number:
[2938169-99-2]
Formula:
C50H60N12O6S2
Target:
PROTACs,Ras
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted