VNPP433-3beta, CAS [[1630820-51-7]]

Catalog Number: MCE-HY-160777
Article Name: VNPP433-3beta, CAS [[1630820-51-7]]
Biozol Catalog Number: MCE-HY-160777
Supplier Catalog Number: HY-160777
Alternative Catalog Number: MCE-HY-160777-5MG,MCE-HY-160777-25MG,MCE-HY-160777-10MG,MCE-HY-160777-1MG,MCE-HY-160777-50MG
Manufacturer: MedchemExpress
Category: Biochemikalien
Alternative Names: Galeterone 3beta-imidazole
VNPP433-3beta (Galeterone 3beta-imidazole) is an orally active molecular glue degrader, which degrades androgen receptor (AR) and its splice variants (AR-Vs) and MAP kinase-interacting serine/threonine protein kinase Mnk1/2. VNPP433-3beta induces cell apoptosis. VNPP433-3beta inhibits tumor growth in the CWR22Rv1 xenograft mouse model. VNPP433-3beta can be used for the study of castration resistant prostate cancer (CRPC) and pancreatic ductal adenocarcinoma (PDAC)[1].
Molecular Weight: 438.61
Purity: 98.01
CAS Number: [1630820-51-7]
Formula: C29H34N4
Target: Androgen Receptor,Apoptosis,MNK,Molecular Glues
Application Notes: MCE Product type: Reference compound