Forodesine (BCX-1777) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine is a potent human lymphocyte proliferation inhibitor. Forodesine could induce apoptosis in leukemic cells by increasing the dGTP levels[1][2].
Molecular Weight:
266.25
Purity:
99.10
CAS Number:
[209799-67-7]
Formula:
C11H14N4O4
Target:
Apoptosis,Nucleoside Antimetabolite/Analog
Application Notes:
Reference compound
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