Nrf2 degrader 1 (compound 1) is a PROTAC Nrf2 degrader with a DC50 of 0.1-1 µM in huH1 cells. Nrf2 degrader 1 inhibits cancer cells growth for A549 and LK-2 cells with IC50 values of 100 nM and 40 nM, respectively. Nrf2 degrader 1 can be used for the study of liver cancer, non-small cell lung cancer (NSCLC) and squamous cell carcinoma of lung cancer[1].
Molecular Weight:
826.92
Purity:
99.12
CAS Number:
[3025286-00-1]
Formula:
C45H42N6O8S
Target:
Keap1-Nrf2,PROTACs
Application Notes:
MCE Product type: Reference compound
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