PSB-KK1415 is a selective GPR18 agonist, with an EC50 of 19.1 nM for human GPR18 and 54.1 nM for murine GPR18. PSB-KK1415 acts as a weak partial agonist of human cannabinoid receptor 1 and 2, with Ki values of 1.18 µM and 0.481 µM, respectively. PSB-KK1415 activates human and murine GPR18, thereby inducing beta-arrestin recruitment. PSB-KK1415 reduces weight gain, induces gastrointestinal disorders and exhibits anorectic activity. PSB-KK1415 can be used in obesity-related research[1][2].
Molecular Weight:
462.93
Purity:
99.92
CAS Number:
[885896-26-4]
Formula:
C24H23ClN6O2
Target:
Cannabinoid Receptor,Transmembrane Glycoprotein
Application Notes:
MCE Product type: Reference compound
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