(S)-PHA533533, CAS [[437982-89-3]]

Product Overview

• Article Name: (S)-PHA533533, CAS [[437982-89-3]]
• Biozol Catalog Number: MCE-HY-162683
• Supplier Catalog Number: HY-162683
• Alternative Catalog Number: MCE-HY-162683-5MG,MCE-HY-162683-1MG,MCE-HY-162683-10MG,MCE-HY-162683-25MG,MCE-HY-162683-50MG,MCE-HY-162683-10MMX1ML
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

(S)-PHA533533 is a CDK2 and CDK5 inhibitor with blood-brain barrier permeability, with IC50 values of 37 nM and 55 nM, respectively. (S)-PHA533533 effectively restores UBE3A expression by downregulating UBE3A-ATS and relieving the epigenetic silencing of paternal UBE3A in mature neurons. (S)-PHA533533 can be used for the research of Angelman syndrome[1].

Product Properties

• Molecular Weight: 338.40
• Purity: 98.27
• CAS Number: [437982-89-3]
• Formula: C19H22N4O2
• Target: CDK,E1/E2/E3 Enzyme

Application Notes

• Application Notes: MCE Product type: Reference compound