G9D-4 TFA is a G9a PROTAC degrader. G9D-4 TFA induces G9a degradation, reduces H3K9me2 levels, and prevents GLP interference via the CRBN ternary complex, proteasome and ubiquitin-like modification-dependent pathways. G9D-4 TFA exerts antiproliferative activity and induces Apoptosis in pancreatic cancer cells. G9D-4 TFA can be used for research on pancreatic cancer[1].
Molecular Weight:
1064.24
Purity:
99.44
Formula:
C55H76F3N9O9
Target:
Apoptosis,Histone Methyltransferase,PROTACs
Application Notes:
MCE Product type: Reference compound
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