ZW-1226, CAS [[2351940-23-1]]

Product Overview

• Article Name: ZW-1226, CAS [[2351940-23-1]]
• Biozol Catalog Number: MCE-HY-162753
• Supplier Catalog Number: HY-162753
• Alternative Catalog Number: MCE-HY-162753-25MG,MCE-HY-162753-5MG,MCE-HY-162753-50MG,MCE-HY-162753-10MG,MCE-HY-162753-100MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

ZW-1226 is a dual Tyrosyl DNA phosphodiesterase 2 (TDP2) and Multidrug resistance-associated protein 1 (MRP1) inhibitor with IC50 values of 0.2 and 0.5 µM, respectively. ZW-1226 exhibits selectivity over other ABC transporters. ZW-1226 elevates intracellular GSH levels, and reverses MRP1-mediated drug resistance. ZW-1226 can be used for the research of leukemia, non-small-cell lung cancer, and multidrug resistant small-cell lung cancer[1][2].

Product Properties

• Molecular Weight: 420.42
• Purity: 98.13
• CAS Number: [2351940-23-1]
• Formula: C25H16N4O3
• Target: P-glycoprotein

Application Notes

• Application Notes: MCE Product type: Reference compound