ZW-1226 is a selective inhibitor of MRP1, reducing the uptake activity of MRP1 vesicles by 65 % at 5 µM. ZW-1226 shows inhibition of MRP1 in a GSH dependent way and good selectivity for MRP1 over other major ABC transporters, including P-gp, BCRP, MRP2 and MRP3[1].
Molecular Weight:
420.42
Purity:
98.13
CAS Number:
[2351940-23-1]
Formula:
C25H16N4O3
Target:
P-glycoprotein
Application Notes:
MCE Product type: Reference compound1
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