AB25583 is a Poltheta helicase (Poltheta-hel) small molecule inhibitor, with an IC50 value of 6 nM. AB25583 selectively kills BRCA1/2 deficient cells and works in synergy with Olaparib (HY-10162) in cancer cells carrying pathogenic BRCA1/2 mutations. AB25583 can be used for tumor research[1].
Molecular Weight:
452.91
Purity:
99.85
CAS Number:
[2565637-94-5]
Formula:
C22H17ClN4O3S
Target:
DNA/RNA Synthesis
Application Notes:
MCE Product type: Reference compound
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