LDN-214117, CAS [[1627503-67-6]]

Product Overview

• Article Name: LDN-214117, CAS [[1627503-67-6]]
• Biozol Catalog Number: MCE-HY-16712
• Supplier Catalog Number: HY-16712
• Alternative Catalog Number: MCE-HY-16712-10MG,MCE-HY-16712-25MG,MCE-HY-16712-10MMX1ML,MCE-HY-16712-50MG,MCE-HY-16712-5MG,MCE-HY-16712-100MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

LDN-214117 is an orally active ALK2 inhibitor with well-tolerated and good brain penetration. LDN-214117 has a high selectivity and low cytotoxicity for ALK2 with an IC50 value of 24 nM. LDN-214117 also is a specific bone morphogenetic proteins (BMPs) signaling inhibitor and has relatively selective inhibition for BMP6 with an IC50 value of 100 nM. LDN-214117 can be used for the research of fibrodysplasia ossificans progressiva (FOP), diffuse intrinsic pontine glioma (DIPG) [1][2].

Product Properties

• Molecular Weight: 419.52
• Purity: 99.54
• CAS Number: [1627503-67-6]
• Formula: C25H29N3O3
• Target: TGF-beta Receptor

Application Notes

• Application Notes: MCE Product type: Reference compound