PQR514 is a potent PI3K inhibitor with anticancer activity. PQR514 is able to inhibit cancer cell proliferation. PQR514 showed significant antitumor activity in the OVCAR-3 xenograft model, with the required concentration being approximately one-eighth that of PQR309. PQR514 has good pharmacokinetic properties and minimal brain penetration, making it an optimized candidate compound for inhibiting systemic tumors[1].
Molecular Weight:
394.38
Purity:
97.73
CAS Number:
[1927857-55-3]
Formula:
C16H20F2N8O2
Target:
PI3K
Application Notes:
MCE Product type: Reference compound
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