PD-1/PD-L1-IN-51 (Compound III-4) is a PD-1/PD-L1 inhibitor (IC50: 2.9 nM for hPD-L1). PD-1/PD-L1-IN-51 directly binds to PD-L1 to block the interaction between PD-1/PD-L1 and enhances IFN-gamma release. PD-1/PD-L1-IN-51 has tumor inhibitory activity[1].
Molecular Weight:
814.28
Formula:
C41H44ClN7O9
Target:
PD-1/PD-L1
Application Notes:
MCE Product type: Reference compound1
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