PROTAC MPS1 degrader 2 (Compound 15) is a potent degrader of monopolar spindle 1 (Mps1, TTK), AURKA and AURKB, with DC50s of 42.0, 2.1 and 154.0 nM, respectively. PROTAC MPS1 degrader 1 can be used for the research of acute myeloid leukemia. (Pink: ligand for target protein (HY-168545), Black: linker (HY-N0420), Blue: ligand for E3 ligase (HY-10984)[1].
Molecular Weight:
847.90
Purity:
99.7800
Formula:
C41H41N11O8S
Target:
Aurora Kinase,Mps1,PROTACs
Application Notes:
MCE Product type: Reference compound
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