Itacitinib (INCB039110) is an orally active and selective inhibitor of JAK1 with an IC50 of 2 nM for human JAK1. Itacitinib shows >20-fold selectivity for JAK1 over JAK2 and >100-fold over JAK3 and TYK2, Itacitinib is used in the research of myelofibrosis[1][2].
Molecular Weight:
553.51
Purity:
99.97
CAS Number:
[1334298-90-6]
Formula:
C26H23F4N9O
Target:
JAK
Application Notes:
MCE Product type: Reference compound
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