PROTAC AR Degrader-9 (Compound c6) is a PROTAC degrader for androgen receptor, that degrades AR in human hair follicle papilla cells (HDPCs) with a DC50 of 262.38 nM. PROTAC AR Degrader-9 promotes the expressions of paracrine factors, such as TGF-beta1 and beta-catenin, exhibits hair regenerating efficacy in mouse models[1]. (Pink: ligand for target protein AR ligand-38 (HY-170450), Black: linker, Blue: ligand for E3 ligase Cereblon (HY-170449))
Molecular Weight:
765.34
Formula:
C43H49ClN6O5
Target:
Androgen Receptor,PROTACs
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
