PROTAC CDK9 degrader-11, CAS [[3039540-19-4]] Preis auf Anfrage

Product Overview

• Article Name: PROTAC CDK9 degrader-11, CAS [[3039540-19-4]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-170978
• Supplier Catalog Number: HY-170978
• Alternative Catalog Number: MCE-HY-170978-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

PROTAC CDK9 degrader-11 (Compound C3) is an orally active PROTAC degrader for CDK9 with DC50 of 1.09 nM. PROTAC CDK9 degrader-11 exhibits cytotoxicity in multi small cell lung cancer cell with IC50 of nanomolar levels. PROTAC CDK9 degrader-11 arrests cell cycle at G0/G1 phase, inhibits the cell invasion in DMS114 and DMS53 cell. PROTAC CDK9 degrader-11 exhibits antitumor efficacy in NCI-H446 xenograft mouse models[1].(Pink: ligand for target protein CDK9 ligand 3 (HY-170979), Black: linker, Blue: ligand for E3 ligase Cereblon E3 ligase Ligand 56 (HY-W247437))

Product Properties

• Molecular Weight: 807.77
• CAS Number: [3039540-19-4]
• Formula: C39H48Cl2N10O5
• Target: CDK,PROTACs

Application Notes

• Application Notes: MCE Product type: Reference compound