LC-04-045

Product Overview

• Article Name: LC-04-045
• Biozol Catalog Number: MCE-HY-172162
• Supplier Catalog Number: HY-172162
• Alternative Catalog Number: MCE-HY-172162-5MG,MCE-HY-172162-100MG,MCE-HY-172162-1MG,MCE-HY-172162-10MMX1ML,MCE-HY-172162-50MG,MCE-HY-172162-25MG,MCE-HY-172162-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

LC-04-045 is a selective NIMA-related kinase 7 (NEK7) molecular glue degrader. LC-04-045 induces NEK7 degradation via the CRBN-based ubiquitin-proteasome system, dependent on the glycine 57-containing degron motif. LC-04-045 inhibits secretion of downstream cytokines IL-1beta and IL-18. LC-04-045 can be used for the research of lymphoblastic leukemia[1].

Product Properties

• Molecular Weight: 566.05
• Purity: 99.56
• Formula: C32H28ClN5O3
• Target: Interleukin Related,Molecular Glues,NEKs

Application Notes

• Application Notes: MCE Product type: Reference compound