EN1441 is a covalent degrader targeting the androgen receptor (AR) with an EC50 value of 4.2 µM and its truncated variant AR-V7. EN1441 selectively and potently degrades both AR and AR-V7 in androgen-independent prostate cancer cells. EN1441 is promising for research of androgen-independent prostate cancers[1].
Molecular Weight:
264.71
Purity:
99.67
CAS Number:
[2196448-47-0]
Formula:
C13H13ClN2O2
Target:
Androgen Receptor
Application Notes:
MCE Product type: Reference compound
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