JP-163-16, CAS [[3100147-70-1]]

Product Overview

• Article Name: JP-163-16, CAS [[3100147-70-1]]
• Biozol Catalog Number: MCE-HY-174864
• Supplier Catalog Number: HY-174864
• Alternative Catalog Number: MCE-HY-174864-10MG,MCE-HY-174864-5MG,MCE-HY-174864-25MG,MCE-HY-174864-1MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

JP-163-16 is a RelA/p65 PROTAC degrader. JP-163-16 selectively reduces the expression of RelA/p65 in a proteasome-dependent manner in cells. JP-163-16 can induce cell apoptosis by inhibiting the NF-kappaB signaling pathway. JP-163-16 can be used for research on RelA/p65-dependent tumours, such as chronic lymphocytic leukaemia (CLL). (Pink: RelA/p65 Ligand (HY-174865), Blue: CRBN Ligand (HY-A0003), Black: Linker, CRBN Ligand+Linker (HY-160241))[1].

Product Properties

• Molecular Weight: 777.86
• Purity: 99.20
• CAS Number: [3100147-70-1]
• Formula: C42H47N7O8
• Target: Apoptosis,NF-kappaB,PROTACs

Application Notes

• Application Notes: MCE Product type: Reference compound1