Mutant IDH1-IN-7 Preis auf Anfrage
Catalog Number:
MCE-HY-175213
| Article Name: |
Mutant IDH1-IN-7 Preis auf Anfrage |
| Biozol Catalog Number: |
MCE-HY-175213 |
| Supplier Catalog Number: |
HY-175213 |
| Alternative Catalog Number: |
MCE-HY-175213-1UNIT |
| Manufacturer: |
MedchemExpress |
| Category: |
Biochemikalien |
| Mutant IDH1-IN-7 is a highly selective Isocitrate Dehydrogenase 1 (IDH1) R132H (IC50 = 0.26 µM, Kd = 2.1 µM)/R132C (IC50 = 1.1 µM) inhibitor. Mutant IDH1-IN-7 has no inhibitory effect on wild-type IDH1, IDH2-wt, and IDH2 R140Q. Mutant IDH1-IN-7 inhibits 2-Hydroxyglutarate (2-HG) production in U87-MG R132H cells (EC50 = 0.55 µM). Mutant IDH1-IN-7 exhibits moderate antiproliferative effects on U87-MG R132H and HT-1080 cells[1]. |
| Molecular Weight: |
456.54 |
| Formula: |
C27H28N4O3 |
| Target: |
Isocitrate Dehydrogenase (IDH) |
| Application Notes: |
MCE Product type: Reference compound |
