AGPAT4-IN-1, CAS [[2411250-59-2]] Preis auf Anfrage

Product Overview

• Article Name: AGPAT4-IN-1, CAS [[2411250-59-2]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-175646
• Supplier Catalog Number: HY-175646
• Alternative Catalog Number: MCE-HY-175646-25MG,MCE-HY-175646-5MG,MCE-HY-175646-10MG,MCE-HY-175646-50MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

AGPAT4-IN-1 (Compound CL26) is a covalent AGPAT4 inhibitor with an IC50 of 795 nM. AGPAT4-IN-1 covalently binds to AGPAT4 at Cys228 and significantly inhibits acyltransferase activity, LPA-to-PA conversion and downstream mTOR/S6K pathways. AGPAT4-IN-1 sensitizes hepatocellular carcinoma (HCC) tumors to Sorafenib (HY-10201) and significantly induces apoptosis with a synergistic response. AGPAT4-IN-1 has antitumor activity and reduces tumorigenicity and stemness in HCC xenograft mouse models[1].

Product Properties

• Molecular Weight: 306.77
• CAS Number: [2411250-59-2]
• Formula: C14H11ClN2O2S
• Target: Acyltransferase,Apoptosis,mTOR,Ribosomal S6 Kinase (RSK)

Application Notes

• Application Notes: MCE Product type: Reference compound