Acalabrutinib (maleate), CAS [[2242394-65-4]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-17600A
Supplier Catalog Number:
HY-17600A
Alternative Catalog Number:
MCE-HY-17600A-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
Calquence (maleate), ACP-196 (maleate)
Acalabrutinib (Calquence) maleate is an orally active, irreversible, and highly selective second-generation BTK inhibitor. Acalabrutinib binds covalently to Cys481 in the ATP-binding pocket of BTK. Acalabrutinib maleate demonstrates potent on-target effects and efficacy in mouse models of chronic lymphocytic leukemia (CLL). Acalabrutinib maleate can be used for CLL research[1][2]. Acalabrutinib maleate is a click chemistry reagent, which contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Molecular Weight:
581.58
CAS Number:
[2242394-65-4]
Formula:
C30H27N7O6
Target:
Btk
Application Notes:
MCE Product type: Reference compound1
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