(E)-Belizatinib, CAS [[1388225-72-6]] Preis auf Anfrage

Product Overview

• Article Name: (E)-Belizatinib, CAS [[1388225-72-6]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-17603A
• Supplier Catalog Number: HY-17603A
• Alternative Catalog Number: MCE-HY-17603A-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: (E)-TSR-011

Product Description

(E)-Belizatinib ((E)-TSR-011)) (compound 36), the (E)-isomer of Belizatinib (HY-17603), is a potent, selective and orally active anaplastic lymphoma kinase (ALK) Inhibitor with an enzymatic IC50 of 0.005 µM and a cellular IC50 of 0.048 µM. (E)-Belizatinib shows >61-fold selectivity over JAK2, SRC, and IGF1R. (E)-Belizatinib shows favorable potency and PK characteristics in rats and dogs. (E)-Belizatinib can be used for ALK-driven cancer research[1].

Product Properties

• Molecular Weight: 577.73
• CAS Number: [1388225-72-6]
• Formula: C33H44FN5O3
• Target: Anaplastic lymphoma kinase (ALK)

Application Notes

• Application Notes: MCE Product type: Reference compound