ACBI-4 is a selective GTP-loaded active state of KRAS (KRAS(on)) PROTAC degrader. ACBI-4 has significant anti-proliferative effect and potently degrades multiple KRAS mutants in cancer cells, such as KRASG12R[1].
Molecular Weight:
970.20
Purity:
97.97
CAS Number:
[3097985-19-5]
Formula:
C50H63N15O4S
Target:
PROTACs,Ras
Application Notes:
MCE Product type: Reference compound
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