LAG-3-IN-1 (Compound 11) is a LAG-3 inhibitor with a KD of 0.41 µM. LAG-3-IN-1 disrupts the LAG-3/MHCII interaction, enhances IFN-gamma secretion and promotes tumor cell killing in cocultures of PBMCs and cancer cells. LAG-3-IN-1 can be used for cancers like ovarian cancer, colon adenocarcinoma and melanoma research[1].
Molecular Weight:
447.57
Formula:
C30H29N3O
Target:
LAG-3
Application Notes:
MCE Product type: Reference compound
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