MRL-SYKi, CAS [[1312534-69-2]]

Product Overview

• Article Name: MRL-SYKi, CAS [[1312534-69-2]]
• Biozol Catalog Number: MCE-HY-178129
• Supplier Catalog Number: HY-178129
• Alternative Catalog Number: MCE-HY-178129-1MG,MCE-HY-178129-5MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

MRL-SYKi is a chemical probe for gain-of-function variants of spleen tyrosine kinase (SYK). MRL-SYKi reduces the catalytic activity of SYKS550Y, SYKS550F and SYKP342T, and downregulates the phosphorylation level of SYKS550Y. MRL-SYKi serves as a template for developing NanoBRET tracers targeting SYK, enabling NanoBRET cellular target engagement assays for gain-of-function variants of SYK. MRL-SYKi is applicable to research related to inflammatory and immune diseases[1].

Product Properties

• Molecular Weight: 452.57
• Purity: 99.9
• CAS Number: [1312534-69-2]
• Formula: C24H28N4O3S
• Target: Syk

Application Notes

• Application Notes: MCE Product type: Reference compound