ROCK2-IN-12, CAS [[3086603-12-2]] Preis auf Anfrage

Product Overview

• Article Name: ROCK2-IN-12, CAS [[3086603-12-2]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-178821
• Supplier Catalog Number: HY-178821
• Alternative Catalog Number: MCE-HY-178821-5MG,MCE-HY-178821-10MG,MCE-HY-178821-1MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

ROCK2-IN-12 (Compound A25) is a selective ROCK2 inhibitor with an IC50 of 7.0 nM for ROCK2 over ROCK1. ROCK2-IN-12 has potent antifibrotic effects via the TGF-beta/Smad and ROCK2/STAT3 signaling pathways. ROCK2-IN-12 significantly reduces collagen deposition and reverses fibrotic progression in Bleomycin (HY-108345)-induced pulmonary fibrosis (PF) mouse models. ROCK2-IN-12 can be used for lung diseases like pulmonary fibrosis research[1].

Product Properties

• Molecular Weight: 455.45
• Purity: 98.02
• CAS Number: [3086603-12-2]
• Formula: C23H18FN9O
• Target: ROCK,STAT,TGF-beta/Smad

Application Notes

• Application Notes: MCE Product type: Reference compound