Nav1.2-IN-2 is a Nav1.2 inhibitor with a human IC50 of 0.18 µM. Nav1.2-IN-2 preferentially binds to the inactivated state of Nav1.2, reduces window current, suppresses neuronal depolarization and action potential generation. Nav1.2-IN-2 suppresses Veratridine (HY-N6691)-induced Ca2+ influx. Nav1.2-IN-2 can be used for the research of epilepsy[1].
Molecular Weight:
322.40
Purity:
99.82
CAS Number:
[7469-49-0]
Formula:
C17H26N2O4
Target:
Calcium Channel,Sodium Channel
Application Notes:
MCE Product type: Reference compound
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