Dyrk1A-IN-16, CAS [[2805339-74-4]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-179600
Supplier Catalog Number:
HY-179600
Alternative Catalog Number:
MCE-HY-179600-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Dyrk1A-IN-16 is a selective, brain-penetrant and ATP-competitive Dyrk1A inhibitor with a IC50 of 53 nM. Dyrk1A-IN-16 displays high selectivity across a broad kinase panel (specific for DYRK kinases) with nanomolar potency. Dyrk1A-IN-16 impairs neurosphere self-renewal, cell invasion, and EGFR stability in vitro. Dyrk1A-IN-16 inhibits tumor growth and prolongs survival in vivo. Dyrk1A-IN-16 has potential for glioblastoma (GBM) research[1].
Molecular Weight:
303.29
CAS Number:
[2805339-74-4]
Formula:
C14H9NO5S
Target:
DYRK,EGFR
Application Notes:
MCE Product type: Reference compound
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