Tan-931 is a non-competitive and selective inhibitor of aromatase , with an IC50 is 17.2 µM and a Ki of 40 µM for human aromatase, and an IC50 of 162 µM for rat aromatase. Tan-931 reduces plasma estradiol-17beta level and weight of ovaries and uterus in PMSG (HY-N12634)-treated female rats. Tan-931 can be used for the research of estrogen-dependent metastatic breast cancer[1][2].
Molecular Weight:
302.24
CAS Number:
[127448-92-4]
Formula:
C15H10O7
Target:
Cytochrome P450
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
