VEGFR-2-IN-79 (Compound 17) is a VEGFR-2 inhibitor with an IC50 of 2.32 µM. VEGFR-2-IN-79 exhibits potent and broad-spectrum cytotoxicity and can induce apoptosis in MCF-7 cells. VEGFR-2-IN-79 does not cause a significant decrease in the mitochondrial membrane potential of MCF-7 cells. VEGFR-2-IN-79 can be used for research on breast cancer[1].
Molecular Weight:
651.04
Formula:
C26H21ClF6N4O3S2
Target:
Apoptosis,VEGFR
Application Notes:
MCE Product type: Reference compound
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