COX-2/5-LOX-IN-6 (Compound 4c) is a potent and selective 5-LOX (IC50 = 0.10 µM) and COX-2 (IC50: 2.88 µM) inhibitor. COX-2/5-LOX-IN-6 displays potent anticancer activity against ovarian cancer. COX-2/5-LOX-IN-6 would not cause cytotoxic effects in noncancerous cells. COX-2/5-LOX-IN-6 is a potential anti-inflammatory agent[1].
Molecular Weight:
517.38
Formula:
C25H23FeN3O4S
Target:
COX,Lipoxygenase
Application Notes:
MCE Product type: Reference compound
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