FXR/HSD17B13-modulator-2 is a highly selective, orally active FXR agonist and HSD17B13 inhibitor, with an EC50 of 128 nM for FXR and an IC50 of 0.18 µM for HSD17B13. FXR/HSD17B13-modulator-2 improves fatty liver, regulates lipid metabolism, reduces inflammation and alleviates liver fibrosis. FXR/HSD17B13-modulator-2 can be used for the research of metabolic dysfunction-associated steatohepatitis[1].
Molecular Weight:
559.46
Formula:
C27H24Cl2N2O5S
Target:
17beta-HSD,FXR
Application Notes:
MCE Product type: Reference compound
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