BMS-561392 (formate), CAS [[2922280-85-9]]

Product Overview

• Article Name: BMS-561392 (formate), CAS [[2922280-85-9]]
• Biozol Catalog Number: MCE-HY-19667A
• Supplier Catalog Number: HY-19667A
• Alternative Catalog Number: MCE-HY-19667A-10MMX1ML,MCE-HY-19667A-5MG,MCE-HY-19667A-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: DPC 333 (formate)

Product Description

BMS-561392 formate (DPC 333 formate) is a selective ADAM17(TACE) inhibitor. BMS-561392 formate inhibits TNF-alpha secretion by regulating signaling pathways such as p44 MAPK and NF-kappaB. BMS-561392 formate also affects the survival of central nervous system-related cells including oligodendrocytes and microglia. BMS-561392 formate promotes microglial apoptosis, enlarges the injury area and exacerbates astrogliosis in a mouse spinal cord injury model. BMS-561392 formate can be used in research related to spinal cord injury and inflammatory diseases[1][2].

Product Properties

• Molecular Weight: 522.59
• Purity: 99.13
• CAS Number: [2922280-85-9]
• Formula: C28H34N4O6
• Target: Apoptosis,NF-kappaB,p38 MAPK,TNF Receptor

Application Notes

• Application Notes: MCE Product type: Reference compound1