Fenebrutinib (GDC-0853) is a potent, selective, orally available, and noncovalent brutons tyrosine kinase (Btk) inhibitor with Kis of 0.91 nM, 1.6, 1.3, 12.6, and 3.4 nM for WT Btk, and the C481S, C481R, T474I, T474M mutants. Fenebrutinib has the potential for rheumatoid arthritis and systemic lupus erythematosus research[1].
Molecular Weight:
664.80
Purity:
99.89
CAS Number:
[1434048-34-6]
Formula:
C37H44N8O4
Target:
Btk
Application Notes:
MCE Product type: Reference compound
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