TTFB, CAS [[352560-76-0]]

Product Overview

• Article Name: TTFB, CAS [[352560-76-0]]
• Biozol Catalog Number: MCE-HY-46286
• Supplier Catalog Number: HY-46286
• Alternative Catalog Number: MCE-HY-46286-1G, MCE-HY-46286-250MG, MCE-HY-46286-500MG, MCE-HY-46286-100MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: N-(4-tert-butyl-1,3-thiazol-2-yl)-3-fluorobenzamide

Product Description

TTFB is a selective, non-competitive zinc-activated channel (ZAC) antagonist. TTFB inhibits Zn- and H-induced ZAC currents with IC50 values of 3 µM and 8.5 µM, respectively, and shows an IC50 of 4.7 µM against spontaneous activity. TTFB exhibits no significant agonistic, antagonistic or modulatory activity towards representative members of classical Cys-loop receptors, including m5-HT3AR, halpha3beta4 nAChR, halpha1beta2gamma2S GABAAR and halpha1 GlyR. TTFB can be used to investigate the physiological and pathological functions of ZAC[1].

Product Properties

• Molecular Weight: 278.35
• Purity: 99.83
• CAS Number: [352560-76-0]
• Formula: C14H15FN2OS
• Target: Others

Application Notes

• Application Notes: MCE Product type: Reference compound